Table 3.

SIV-dependent decrease in miR expression that is increased by chronic THC compared to VEH. miR names, validated or predicted target genes are shown.

Category 3 – Decreased miR expression due to SIV, and THC increases it more than VEH	hsa-miR-137	RAPGEF5, ZNF295, RREB1, SIK1, SLC12A2, SNRK, C21orf91, STK40, NCOA3, MED11, TMLHE, GBP3, ZNF343, SH3TC1, IFIT3, C8orf84, CCDC126, C16orf46, SSR3, SPTLC3, TIGD1, COCH, DTNA, DMRTA1, ERLIN2, MED27, GLIPR1, NOX4, ICA1L, SGK494, STATH, TCTN3, PIGY, ZNF621, TBCE, PROL1, SUSD3, DMRT2, TBC1D19, AP3S1, ACSBG2, TXNDC17, TULP3, BRAF, C17orf58, DFFB, PARP4, TMSB15B, RNLS, C3orf64, TNFAIP6, ZNF789AP, RPS13, AQPEP, KIAA1383, WARS2, ANGPT1, HTN1, HTN3, WNT16, PPAPDC1B, FTHL17, DOCK8, C1QTNF7, PTN, ALPI, PXDNL, AFM, RPL11, PRSS16, RHOBTB1, RECQL, ARHGAP24, MTFR1, SMCP,NAALAD2, AGPAT5, ALDH8A1, REG3A,, ZNF124, HLA-DQA2, PCDHB7, DSG3, ALPPL2, CASP3, SIP1, HSD3B2, CCNL2, PLAC8, TJP2, GDPD1, RAD51B, SCAMP1, MAGEA6, UGT2B10, MAPK10, MSRB3, ESRRG, ESRRA, NXT2, COL19A1, SHROOM2, MITF, RAVER2, FNDC5, USP30, HLTF, C20orf111, ZNF710, SLC43A2, NEUROD4, AHCYL2, MPP1, MBD2, KIAA0907, KIT, CCNG2, SERP1, PRR16, HNRPDL, PRADC1, ZAK, ARHGEF18, INPP5A, KDM4A, GPCPD1, TMEM56, SLC6A8, MBTPS2, CYYR1, CXCL12, SLC35A1, SLC4A7, PARP8, TBC1D1, ABHD6, TAF7L, SGCG, NIPBL, SLC35A4, EFR3A, KIAA1409, PRKAB2, ZCCHC2, IFT20, FAM126B, E2F6, NCK1, PDLIM3, TCF12, GCA, SLC16A6, APLN, NEUROD1, GJC1, SNX25, SLC1A5, C3orf58, DR1, SWT1, RWDD4, BAZ1A, C10orf26, MAP3K14, NCOA2, TTC26, PDCD6, PRDM1, C20orf26, CNTN3, FMNL2, KLF15, ATP10A, PIAS2, NRXN3, ABI3BP, APPL2, MBNL2, VPS37A, NEFH, CDC37L1, DDX3X, RAB9A, CLDN22, PABPC4L, HMGN3, TDRD7, ABHD5, NCKAP5, DMRT3, SLMAP, CEP128, CSE1L, STK3, E2F7, C17orf103, TRIM23, KLHL10, KDELR3, CDK6, CDC42, CTBP1, PTGS2, ZNF804A, YBX1, CSE1L, PXN
	mml-miR-7_R+1	IGF1R, CAPZA1, IDE, VPS26A, SLC25A15, ARF4, PFN2, CNO, ZNF549, MMAA, ZNF425, CLEC4M, FPGT, H2AFV, ABCA13, B3GALTL, AQPEP, FCHO2, ZNF557, COLEC12, GLTPD1, DTYMK, ZSCAN29, MOSPD1, TFF3, DLEU7, TMEM97, POLI, INF2, EGLN3, FIGF, GABRA6, REG3G, LRRC8E, IL17RB, TM7SF4, SYNC, ANKRD36B, PRDM6, LOC100287036, ZNF275, ADAMDEC1, LILRA6, INPP5B, DHRS7B, MMEL1, MAPKAP1, DNAH14, SCARB2, NAPG, NQO1, SERPINB5, ACER3, TSPYL4, TLR4, CCDC64B, LNX2, APOA2, TTLL6, GRIN2C, ZNF329, FSD2, QTRTD1, FAM164C, GREM1, KRT74, SDHC, TREM1, ATG4C, NXF1, FAM71E1, ZNF75A, FAM115C, SPATA2, RAF1, POLE4, ZNF828, IRS2, UBXN2B, FOXN3, ZNF395, CACNG7, ZC3H4, SNCA, FAM168B, GJC1, HDLBP, ARID4A, RNF141, KIF16B, C5orf22, PSME3, PIK3CD, CCDC76, SLC6A9, KLF4, SLC25A15, CUL5, SLIT1, GLI3, CNPPD1, ATG4A, LEMD3, NDUFA4, ADAM11, CKAP4, CTSB, PIGH, EGFR, NXT2, PARP1, WASF3, CNOT8, UBLCP1, C1orf226, SMC1A, CAMKK2, VDAC1, C2orf63, ISY1, ITPKC, PTAR1, PRKCB, EIF4EBP2, GEN1, PLAC4, NF2, IDE, CCNI2, RB1, FLJ45513, NSL1, UBE2D4, WDR47, PKP2, UBQLN4, LRRC59, SH3GLB1, TBC1D12, CTSK, OSBPL3, TRIM58, TMEM168, C6orf64, CNOT6, RELA, FAM131B, AMOT, CISD2, UGT3A1, C10orf57, MESDC2, TMEM43, LRRC16A, ACSL4, PAN2, CXorf40A, CD69, DNAJC15, UMPS, FRMD4B, PRR18, CLEC1A, FBXL7, LECT1, RUSC1, TBC1D2B, KRTAP7-1, NDST3, TMX4, GATA5, ZFYVE20, SLC4A7, CALM3, GRP, NR4A3, TAB2, CDK1, KRTAP5-4, ZMYND12, ACTC1, DET1, EXOSC2, FCGR3A, FCGR3B, RGS21, SMUG1, DISC1, UBR5, FNDC4, HERPUD2, HMGN4, CCDC66, RBMX, DSEL, KIAA1919, LOC100132963, MS4A7, EDAR, SLC16A7, TLCD2, RYK, HLA-DOB, SAV1, BTLA, ERLIN2, DCAF12L2