Skip to main content
. 2016 Mar 1;11(3):e0149661. doi: 10.1371/journal.pone.0149661

Table 2. Prognostic value of clinicopathological variables in predicting disease free survival using univariate and multivariate Cox model.

Variables Univariate Cox Analysis (DFS) Multivariate Cox Analysis (DFS)
HR (95%CI) p-value HR (95%CI) p-value
Age 1.020 (0.999–1.038) 0.061 - -
Pathology, tumor stage, pT 1.877 (1.281–2.75) 0.001 5.104 (1.468–17.748) 0.0103
Pathology, nodal stage, pN 1.728 (1.231–2.425) 0.001 3.389 (1.511–7.601) 0.0031
Pathology, Stage Group 1.988 (1.272–3.106) 0.002 - -
EGFR %, continuous 1.012 (1.002–1.022) 0.021 - -
    ≤15% vs > 15% 4.066 (1.607–10.29) 0.003 6.124(1.400–26.786) 0.0161
CK5/6%, continuous 1.01 (1.001–1.019) 0.034 - -
    ≤ 50% vs > 50% 2.308 (1.248–4.27) 0.008 2.678 (1.187–6.044) 0.0177
P53%, continuous 0.994 (0.990–1.010) 0.902 - -
    ≤ 50% vs > 50% 1.028 (0.513–2.061) 0.938 - -
Ki-67%, continuous 1.011 (0.990–1.024) 0.122 - -
    ≤50% vs >50% 1.503 (0.834–2.707) 0.175 2.367(1.005–5.574) 0.0487