Table 2. Prognostic value of clinicopathological variables in predicting disease free survival using univariate and multivariate Cox model.
Variables | Univariate Cox Analysis (DFS) | Multivariate Cox Analysis (DFS) | ||
---|---|---|---|---|
HR (95%CI) | p-value | HR (95%CI) | p-value | |
Age | 1.020 (0.999–1.038) | 0.061 | - | - |
Pathology, tumor stage, pT | 1.877 (1.281–2.75) | 0.001 | 5.104 (1.468–17.748) | 0.0103 |
Pathology, nodal stage, pN | 1.728 (1.231–2.425) | 0.001 | 3.389 (1.511–7.601) | 0.0031 |
Pathology, Stage Group | 1.988 (1.272–3.106) | 0.002 | - | - |
EGFR %, continuous | 1.012 (1.002–1.022) | 0.021 | - | - |
≤15% vs > 15% | 4.066 (1.607–10.29) | 0.003 | 6.124(1.400–26.786) | 0.0161 |
CK5/6%, continuous | 1.01 (1.001–1.019) | 0.034 | - | - |
≤ 50% vs > 50% | 2.308 (1.248–4.27) | 0.008 | 2.678 (1.187–6.044) | 0.0177 |
P53%, continuous | 0.994 (0.990–1.010) | 0.902 | - | - |
≤ 50% vs > 50% | 1.028 (0.513–2.061) | 0.938 | - | - |
Ki-67%, continuous | 1.011 (0.990–1.024) | 0.122 | - | - |
≤50% vs >50% | 1.503 (0.834–2.707) | 0.175 | 2.367(1.005–5.574) | 0.0487 |