Table 2. BMI change following olanzapine treatment.
Total (n = 31) | Male (n = 12) | Female (n = 19) | |||||||
---|---|---|---|---|---|---|---|---|---|
Baseline | Endpoint | P | Baseline | Endpoint | P | Baseline | Endpoint | P | |
Olanzapine dose, mg/day* | 0.0 ± 0.0 | 12.4 ± 7.1 | - | 0.0 ± 0.0 | 13.8 ± 8.6 | - | 0.0 ± 0.0 | 11.6 ± 6.0 | - |
Duration of olanzapine medication, weeks* | 0.0 ± 0.0 | 37.0 ± 27.5 | - | 0.0 ± 0.0 | 33.6 ± 33.5 | - | 0.0 ± 0.0 | 39.0 ± 24.0 | - |
BPRS* | 32.6 ± 7.9 | 26.2 ± 7.3 | .004† | 35.9 ± 6.2 | 31.7 ± 6.2 | NS† | 30.0 ± 8.3 | 22.8 ± 5.7 | .031† |
BMI, kg/m2* | 20.7 ± 3.0 | 22.8 ± 3.9 | < .001† | 21.0 ± 3.6 | 22.5 ± 3.9 | .008† | 20.5 ± 2.6 | 23.0 ± 3.9 | .003† |
*Data are expressed as mean ± standard deviation.
†Paired t-test was used.
Abbreviations: BPRS, Brief Psychiatric Rating Scale; BMI, body mass index; NS, not significant.