Table 4. Univariate and multivariate Cox regression analyses of disease-specific survival using PET parameters.

Variables	Univariate analysis		Multivariate analysisa
	HR (95% CI)	P	HR (95% CI)	P
PET/HCT
SUV entropy	2.69 (1.37–5.29)	0.004	2.69 (1.32–5.45)	0.006
Entropy	2.81 (1.34–5.92)	0.006	2.69 (1.23–5.89)	0.013
Coarseness	0.38 (0.19–0.76)	0.007	0.34 (0.15–0.79)	0.012
PET/ACT
SUV entropy	2.49 (1.24–4.99)	0.010	2.77 (1.32–5.83)	0.007
Entropy	2.81 (1.34–5.92)	0.006	2.69 (1.23–5.89)	0.013
Coarseness	0.38 (0.19–0.76)	0.007	0.34 (0.15–0.79)	0.012

HR: hazard ratio; CI: confidence interval.

^aAdjusted for age, cell type, radical surgery, and AJCC stage (see text).