Table 5. Univariate and multivariate Cox regression analyses of disease-specific survival using PET parameters with tumor segmented with the T45 approach.
| Variables | Univariate analysis | Multivariate a | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| PET/HCT | ||||
| SUV entropy | 3.16 (1.58–6.35) | 0.001 | 3.26 (1.52–6.99) | 0.002 |
| Entropy | 4.52 (1.74–11.78) | 0.002 | 3.87 (1.47–10.22) | 0.006 |
| Coarseness | 0.46 (0.20–1.05) | 0.066 | 0.42 (0.18–1.02) | 0.056 |
| PET/ACT | ||||
| SUV entropy | 2.47 (1.20–5.09) | 0.014 | 2.81 (1.29–6.09) | 0.009 |
| Entropy | 3.74 (1.54–9.09) | 0.004 | 3.13 (1.27–7.73) | 0.013 |
| Coarseness | 0.28 (0.11–0.72) | 0.008 | 0.26 (0.10–0.69) | 0.007 |
HR: hazard ratio; CI: confidence interval.
aAdjusted for age, cell type, radical surgery and AJCC stage (see text).