Table 1. Characteristics of all participants, and divided into obese and non-obese.
Exploratory cohort (DNBC) | Replication cohort (ALSPAC) | |||||
---|---|---|---|---|---|---|
All | Obese | Non-obese | All | Obese | Non-obese | |
N | 2,118 | 990 | 1,128 | 4,841 | 238 | 4,603 |
Maternal age at conception, years | 30 (24, 38) | 30 (24, 38) | 30 (24, 38) | 28 (21, 36) | 28 (20, 37) | 28 (21, 36) |
BMI | 30.1 (19.4, 41.0) | 35.7 (33.4, 43.0) | 22.5 (18.7, 29.7) | 22.2 (18.7, 29.8) | 32.7 (30.2, 41.33) | 22.0 (18.6, 27.4) |
GWG, kg | 13 (4, 25) | 10 (3, 25) | 15 (8, 25) | 16.6 (8.2, 25.5) | 13.1 (0.8, 24.3) | 16.7 (8.7, 25.6) |
Gestational age at birth, weeks | 40 (37, 42) | 40 (37, 42) | 40 (37, 42) | 40 (38, 42) | 40 (37, 42) | 40 (38,42) |
Primiparous, % | 49.8 | 49.2 | 50.4 | 50.6 | 42 | 51 |
Total energy, kJ/day | 9,640 (6,068, 14,518) | 9,174 (5,783, 14,304) | 9,951 (6,360, 14,618) | 7,157 (4,407, 10,579) | 6,483 (3,886, 10,184) | 7,181 (4,444, 10,622) |
Fatty fish, weekly servings | 0.0 (0.0, 1.1) | 0.0 (0.0, 0.9) | 0.0 (0.0, 1.3) | 0.4(0, 1.4) | 0.4 (0, 1.4) | 0.4 (0, 1.4) |
Lean fish, weekly servings | 0.5 (0, 2.1) | 0.3 (0, 2) | 0.5 (0.0, 2.4) | 0.7 (0, 2.0) | 0.4 (0, 2.9) | 0.7 (0, 2.0) |
Total fish, weekly servings | 0.6 (0, 3.0) | 0.5 (0, 2.8) | 0.8 (0.0, 3.4) | 1.6 (0, 3.5) | 1.1 (0, 4.4) | 1.6 (0, 3.5) |
n-3 fatty acids (g/day) | 0.6 (0.3, 1.2) | 0.6 (0.3, 1.1) | 0.7 (0.4, 1.2) | NA | NA | NA |
n-6 fatty acids (g/day) | 2.5 (1.2, 4.3) | 2.5 (1.3, 4.3) | 2.6 (1.3, 4.3) | NA | NA | NA |
Non-smokers, % | 85.1 | 85.5 | 84.7 | 81.9 | 80.2 | 82 |
Low social-occupational status, % | 12.4 | 16.3 | 8.9 | 16.4 | 22.7 | 16.1 |
Alcohol, % non-drinkers | 60.3 | 69.2 | 52.2 | 43.4 | 50.8 | 43 |
Physically inactive, % | 64.9 | 67.5 | 62.4 | 32.6 | 31.1 | 32.7 |
GRS | 28 (23, 34) | 29 (23, 34) | 28 (22, 34) | NA | NA | NA |
Abbreviations: BMI, body mass index; GWG, gestational weight gain; GRS, sum of the BMI-associated risk alleles