Table 4. Distribution of the genotypes of the analysed polymorphisms and the frequency of restenosis in relation to genotypes in the analysed cohort.
| Gene/Polymorphism | Homozygous major | Heterozygous | Homozygous minor | P value | MAF | MAF EU population [32] | |
|---|---|---|---|---|---|---|---|
| TGFB1 (rs1800470) | Genotype frequency, n(%) | 83 (32) | 122 (47.1) | 54 (20.9) | 44% | 38% | |
| Restenosis, n (%) | 11 (13.3) | 31 (25.4) | 10 (18.5) | 0.09 | |||
| PDGFB (rs2285094) | Genotype frequency, n (%) | 37 (14.0) | 124 (46.8) | 104 (39.2) | 47% | 46% | |
| Restenosis, n (%) | 10 (27.0) | 21 (16.9) | 22 (21.2) | 0.38 | |||
| EGF (rs4444903) | Genotype frequency, n(%) | 94 (35.5) | 109 (41.1) | 62 (23.4) | 44% | 39% | |
| Restenosis, n (%) | 19 (19.1) | 22 (20.2) | 13 (21.0) | 0.98 | |||
| bFGF (rs308395) | Genotype frequency, n(%) | 210 (79.5) | 51 (19.3) | 3 (1.2) | 11% | 16% | |
| Restenosis, n (%) | 42 (20.0) | 10 (19.6) | 1 (33.3) | 0.71 | |||
| VEGF-A (rs699947) | Genotype frequency, n(%) | 77 (29.2) | 123 (46.6) | 64 (24.2) | 48% | 50% | |
| Restenosis, n (%) | 19 (24.7) | 22 (17.9) | 12 (18.8) | 0.48 |
Abbreviations: EU–European, TGFB1 –transforming growth factor beta 1, PDGFB—platelet-derived growth factor beta polypeptide, EGF–epidermal growth factor, bFGF–basic fibroblast growth factor, VEGF-A–vascular endothelial growth factor A.