Fig. 2. Adjusted odds ratios showing the relationship between high serum anti-dust EV IgG levels and the risk of asthma subtypes/COPD severity/lung cancer subtypes. Multiple linear logistic regression analyses after adjustment for age, gender, and cigarette smoking history were performed on 294 asthma, 242 COPD, and 325 lung cancer patients vs 90 control subjects. Asthma was divided into non-atopic and atopic asthma according to positive skin prick test responses to common inhalant allergens, and into non-eosinophilic and eosinophilic asthma according to sputum eosinophil percentage (3%). COPD were divided into into tertile subgroups according to lung function. Lung cancer was classified as main cellular subtypes, namely, squamous cell carinoma, adenocarcinoma, and small cell lung cancer. Serum anti-dust EV IgG levels were deemed to be high when they exceeded the 95 percentile value of the control subjects. *P<0.05 vs the control group.
