Table 2. Association of IgG sensitization to dust EVs with asthma, COPD, and lung cancer by multivariable analysis.

	Asthma			COPD			Lung cancer
	Odds ratio	95% CI	P value†	Odds ratio	95% CI	P value†	Odds ratio	95% CI	P value†
Aging	1.03	1.01-1.05	0.002	1.2	1.1-1.2	<0.001	1.2	1.1-1.2	<0.001
Female gender	0.7	0.3-1.5	0.352	1.0	0.3-2.8	0.93	0.7	0.3-1.8	0.45
Cigarette smoking	0.3	0.1-0.6	0.001	3.7	1.4-10.1	0.01	2.7	1.1-7.0	0.03
Anti-EV IgG*	3.3	1.1-10.0	0.039	8.0	2.0-3.25	0.003	38.7	10.4-144.3	<0.001

^*The positive rate of IgG sensitization to dust EVs, based on a high anti-dust EV IgG level in serum; ^†Logistic regression analysis vs the control group.