Table 4. Risk of IgG sensitization to dust EVs to asthma subtype expression.
Non-atopic (n=115) | Atopic (n=87) | Non-eosinophilic‡ (n=115) | Eosinophilic (n=104) | |||||
---|---|---|---|---|---|---|---|---|
Odds ratio (95% CI) | P value† | Odds ratio (95% CI) | P value† | Odds ratio (95% CI) | P value† | Odds ratio (95% CI) | P value† | |
Aging | 1.1 (1.0-1.1) | <0.001 | 1.0 (1.0-1.0) | 0.27 | 1.0 (1.0-1.0) | 0.01 | 1.0 (1.0-1.0) | 0.01 |
Female gender | 1.8 (0.7-4.6) | 0.25 | 0.5 (0.2-2.2) | 0.14 | 0.8 (0.3-1.8) | 0.53 | 0.6 (0.2-1.4) | 0.20 |
Cigarette smoking | 0.6 (0.2-1.6) | 0.29 | 0.3 (0.1-0.6) | <0.001 | 0.3 (0.1-0.8) | 0.01 | 0.2 (0.1-0.6) | <0.001 |
Anti-EV IgG* | 2.8 (0.8-9.6) | 0.1 | 2.9 (0.9-9.8) | 0.08 | 3.7 (1.1-12.3) | 0.03 | 3.1 (0.8-11.4) | 0.10 |
*High serum IgG against dust EVs; †Linear logistic regression analysis vs the control group; ‡The percentage of eosinophils in sputum < 3%.