Table 6. Risk of IgG sensitization to dust EVs to the expression of COPD severity.

	Mild (n=80)		Moderate (n=82)		Severe (n=80)
	Odds ratio (95% CI)	P value†	Odds ratio (95% CI)	P value†	Odds ratio (95% CI)	P value†
Aging	1.2 (1.1-1.2)	<0.001	1.2 (1.1-1.2)	<0.001	1.2 (1.1-1.3)	<0.001
Female gender	0.6 (0.2-2.1)	0.44	1.8 (0.4-7.6)	0.45	0.3 (0.03-3.1)	0.31
Cigarette smoking	1.6 (0.5-4.9)	0.42	8.9 (2.2-36.2)	0.002	119.0 (5.9-2,389.8)	0.002
Anti-dust EV IgG*	7.1 (1.5-33.4)	0.01	12.2 (2.4-61.5)	0.002	50.3 (1.9-1,316.0)	0.02

^*High serum IgG against dust EVs; ^†Linear logistic regression analysis vs the control group.