Table 8. Risk of IgG sensitization to dust EVs to lung cancer subtype expression.
Squamous cell (n=94) | Adenocarcinoma (n=90) | Small cell (n=70) | ||||
---|---|---|---|---|---|---|
Odds ratio (95% CI) |
P value† | Odds ratio (95% CI) |
P value† | Odds ratio (95% CI) |
P value† | |
Aging | 1.2 (1.1-1.3) | <0.001 | 1.2 (1.1-1.2) | <0.001 | 1.2 (1.1-1.3) | <0.001 |
Female gender | 0.1 (0.0-0.8) | 0.03 | 1.8 (0.5-6.8) | 0.37 | 0.3 (0.1-1.5) | 0.15 |
Cigarette smoking | 6.5 (1.5-29.0) | 0.01 | 2.8 (0.7-10.1) | 0.13 | 9.1 (2.0-41.3) | 0.004 |
Anti-EV IgG (+)* | 81.1 (10.4-631.2) | <0.001 | 27.2 (7.4-99.7) | <0.001 | 61.6 (9.0-421.6) | <0.001 |
*High serum IgG against dust EVs; †Linear logistic regression analysis vs the control group.