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. 2016 Mar 1;11(3):e0149872. doi: 10.1371/journal.pone.0149872

Table 3. Association between the co-expression of pWee1 and γ-H2AX and A) Pathological complete response (N = 52), B) Death (N = 8).

Pathological complete response
A) N = 52 No Yes Chi2
N (%) N (%) P-value
pWee1neg / γ-H2AXcat low 7 (43.8) 9 (56.3) 0.009
pWee1neg /γ-H2AXcat high or pWee1pos /γ-H2AXcat low 14 (70.0) 6 (30.0)
pWee1pos /γ-H2AXcat high 15 (93.8) 1 (6.2)
Death
B) N = 8 No Yes Chi2
N (%) N (%) P-value
pWee1neg /γ-H2AXcat low 15 (93.8) 1 (6.2) 0.013
pWee1neg /γ-H2AXcat high or pWee1pos /γ-H2AXcat low 19 (95.0) 1 (5.0)
pWee1pos /γ-H2AXcat high 10 (62.5) 6 (37.5)

pWee1, phosphorylated Wee1-like protein kinase; γ-H2AX, phosphorylated H2A Histone Family Member X