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. 2016 Mar 1;11(3):e0149872. doi: 10.1371/journal.pone.0149872

Table 4. Uni and multivariate logistic regression models of patient- and disease-related features and pathological complete response.

Univariate logistic regression model Multivariate logistic regression model*
OR (95%CI) P-value OR (95%CI) P-value
Variables
Age >45.5 vs ≤45.5 0.70 (0.21–2.28) 0.549
Stage II-III vs I 1.36 (0.40–4.69) 0.623
Histology AC vs SCC Not applicable Not applicable
CT cycles 4 vs 3 2.46 (0.71–8.52) 0.156
γ-H2AX high vs low 4.20 (1.13–15.59) 0.032 7.14 (1.30–39.29) 0.024
pWee1 pos vs neg 5.31 (1.42–19.87) 0.013 8.92 (1.68–47.26) 0.010

* Adjusted for age, stage, number of chemotherapy cycles.

AC, Adenocarcinoma; SCC: Squamous cell carcinoma; CT, Chemotherapy.