Table 4. Uni and multivariate logistic regression models of patient- and disease-related features and pathological complete response.
Univariate logistic regression model | Multivariate logistic regression model* | ||||
---|---|---|---|---|---|
OR (95%CI) | P-value | OR (95%CI) | P-value | ||
Variables | |||||
Age | >45.5 vs ≤45.5 | 0.70 (0.21–2.28) | 0.549 | ||
Stage | II-III vs I | 1.36 (0.40–4.69) | 0.623 | ||
Histology | AC vs SCC | Not applicable | Not applicable | ||
CT cycles | 4 vs 3 | 2.46 (0.71–8.52) | 0.156 | ||
γ-H2AX | high vs low | 4.20 (1.13–15.59) | 0.032 | 7.14 (1.30–39.29) | 0.024 |
pWee1 | pos vs neg | 5.31 (1.42–19.87) | 0.013 | 8.92 (1.68–47.26) | 0.010 |
* Adjusted for age, stage, number of chemotherapy cycles.
AC, Adenocarcinoma; SCC: Squamous cell carcinoma; CT, Chemotherapy.