Figure 1.

Changes in mRNA expression of PGC1α after palmitate treatment. A. The mRNA of PGC1α showed incubation time-related changes following 500 μM of palmitate treatment, and maximum expression (15.7‑fold change vs. control) was observed with 12 h of treatment. B. The mRNA of PGC1α showed dose-related changes (100 to 1000 μM), and maximum expression (12.5‑fold change vs. control) was observed at a dose of 500 μM after 12 h of palmitate treatment. Data are expressed as mean ± standard deviation. Four independent experiments were performed to generate the results. PA, palmitate