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. 2016 Feb 11;13(3):169–178. doi: 10.7150/ijms.13581

Figure 4.

Figure 4

Regulation of mRNA expression of PPARγ by PGC1α. A. The mRNA expression of PGC1α after 12 h of treatment with 500 μM palmitate showed a significant decrease in Huh7 cells transfected with siRNA against PGC1α (0.17‑fold vs. control transfected with scRNA). B. The mRNA expression of PGC1α after 24 h of treatment with 500 μM palmitate showed a significant decrease in Huh7 cells transfected with siRNA against PGC1α (0.23‑fold vs. control transfected with scRNA). C. The mRNA expression of PPARγ after 12 h of treatment with 500 μM palmitate showed a significant decrease in Huh7 cells after transfection with siRNA against PGC1α (0.51‑fold vs. control transfected with scRNA). D. The mRNA expression of PPARγ after 24 h of treatment with 500 μM palmitate showed a significant decrease in Huh7 cells after transfection with siRNA against PGC1α (0.46‑fold vs. control transfected with scRNA). Data are expressed as mean ± standard deviation. Six independent experiments were performed to generate the results. PA, palmitate.