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Anabolic (aggrecan, collagen II, TIMP-1 and TIMP-3) and catabolic (ADAMTS-4 and MMP-3) gene expression analysis. Gene expression of immature nucleus pulposus (NP) cells in different compressive magnitude groups (A), compressive frequency groups (B) and compressive duration groups (C). Data are expressed as the means ± SD, n=3. #: Indicates a significant difference (p<0.05) compared with the control group (p<0.05) between two groups.
