Subject area	Biology/Neurosciences
More specific subject area	Immunology
Type of data	Text, figures with microscopy images and graphs, tables
How data was acquired	Microscope (Zeiss PALM Axiovert 200M), Real-time PCR system (Step One Plus Real-Time PCR System, Applied Biosystems), Spectrophotometer (Spectramax Plus 384, Molecular Devices). Results were analyzed using GraphPad Prism software
Data format	Analyzed
Experimental factors	Mice were intravenously injected with brain-targeted stable nucleic acid lipid particles
Experimental features	Mouse serum, mouse brain sections and mouse cerebellar homogenates were analyzed to evaluate the immune response
Data source location	Center for Neurosciences and Cell Biology, University of Coimbra, Coimbra, Portugal
Data accessibility	Data is supplied in this article