Table 2.
Results of Sonazoid-enhanced ultrasonography for patients with hepatic metastasis of breast cancer
| B-mode | Sonazoid | CECT | MRI | B-mode | Sonazoid | |
|---|---|---|---|---|---|---|
| No. false positive cases | ||||||
| Total lesions of suspected metastasesa | 84 | 84 | 84 | 84 | ||
| Total detected lesion | 56 | 83 | 80 | 84 | ||
| Total lesions of MBCb | 79 | 79 | 79 | 79 | ||
| Detected No. MBC | 51 | 78 | 75 | 79 | ||
| Detected No. other diseases | 5 | 0 | ||||
| Hemangioma | 0 | 3 | 3 | 3 | 3 | 0 |
| Focal fatty change | 0 | 2 | 2 | 2 | 2 | 0 |
| Sensitivity (%)c | 66.7 | 98.8 | 95.2 | 100 | ||
| Accuracy (%)c | 64.6 | 98.7 | 94.9 | 100 | ||
| Positive predictive rate (%) | 70.9 | 98.7 | ||||
| False positive rate (%) | 6.3 | 0 | ||||
| False negative rate (%) | 29.1 | 1.3 | ||||
a24 patients with total 84 hepatic tumors having or suspected of having metastatic cancer from breast cancer
b19 patients with a total 79 metastatic breast cancer (MBC) lesions, diagnosed through contrast-enhanced MRI and/or CECT
cStatistical significance