Table 1.
Descriptive data for MESA participants whose data was used in this study. Data are presented as n (%) for binary measures or median [IQR] for continuous measure.
| Participant characteristicsa | EUA | CHN | AFA | HIS |
|---|---|---|---|---|
| No. subjects | 2329 | 691 | 2482 | 2012 |
| Women | 1212 (52.0) | 349 (50.5) | 1394 (56.2) | 1085 (53.9) |
| Age, years | 63 [54, 71] | 63 [54, 71] | 60 [53, 68] | 60 [53, 68] |
| BMI, kg/m2 | 27.0 [24.2, 30.3] | 23.7 [21.7, 26.0] | 29.4 [26.1, 33.8] | 28.6 [25.9, 32.0] |
| Fasting glucose, mg/dL | 87 [81, 95] | 92 [85, 101] | 92 [84, 102] | 93 [85, 105] |
| Hypertension | 899 (38.6) | 262 (37.9) | 1489 (60.0) | 830 (41.3) |
| Diabetes status | 128 (5.5) | 90 (13.0) | 423 (17.0) | 369 (18.3) |
| Lipid medication | 422 (18.1) | 94 (13.6) | 459 (18.5) | 333 (16.6) |
| Current smoking | 264 (11.3) | 37 (5.4) | 480 (19.3) | 272 (13.5) |
| Lipid levelsa | ||||
| HDL cholesterol, mg/dL | 50 [41, 61] | 48 [40, 56] | 50 [42, 61] | 46 [39, 55] |
| LDL cholesterol, mg/dL | 115 [95, 136] | 114 [96, 132] | 115 [95, 137] | 118 [96, 139] |
| Total cholesterol, mg/dL | 194 [172, 216] | 191 [171, 209] | 188 [165, 212] | 195 [171, 220] |
| Triglycerides, mg/dL | 113 [77, 162] | 122 [86, 170] | 88 [65, 121] | 135 [95, 189] |
| Subclinical atherosclerosis | ||||
| Common carotid IMT, mm | 0.84 [0.73, 0.97] | 0.81 [0.70, 0.92] | 0.86 [0.76, 0.99] | 0.81 [0.71, 0.93] |
| Internal carotid IMT, mm | 0.89 [0.72, 1.39] | 0.73 [0.60, 0.94] | 0.91 [0.70, 1.30] | 0.83 [0.68, 1.19] |
| CAC prevalence | 1325 (56.9) | 356 (51.5) | 1063 (43.2) | 926 (46.3) |
| CAC Agatston scoreb | 115.7 [23.9, 372.4] | 66.4 [21.2, 194.5] | 71.7 [17.9, 267.0] | 77.3 [20.1, 285.1] |
a
Sample sizes are reported for participants included in genetic analysis (e.g. participants with all covariates available).
b
Agatston score values are reported for participants with CAC>0.