Table 2.
Variables | Group | Baseline | HS | 60 min | 120 min |
---|---|---|---|---|---|
MAP (mm Hg) | Blank | 131 ± 7 | 37 ± 16∗ | 67 ± 23∗ | 88 ± 24 |
Normal saline | 122 ± 6 | 39 ± 13∗ | 61 ± 25∗ | 78 ± 27∗ | |
G-CSF | 120 ± 9 | 35 ± 14∗ | 70 ± 29∗ | 89 ± 17 | |
Unres/G-CSF | 125 ± 6 | 37 ± 11∗ | 36 ± 13∗ | 34 ± 14∗ | |
| |||||
HR (beat/min) | Blank | 382 ± 7 | 435 ± 26∗ | 429 ± 21∗ | 411 ± 20 |
Normal saline | 367 ± 10 | 451 ± 19∗ | 438 ± 20∗ | 419 ± 19 | |
G-CSF | 371 ± 11 | 448 ± 22∗ | 435 ± 26∗ | 415 ± 23 | |
Unres/G-CSF | 385 ± 9 | 440 ± 27∗ | 406 ± 29∗ | 402 ± 18 | |
| |||||
HGB (g/L) | Blank | 97.9 ± 19.2 | 91.5 ± 15.6 | 81.4 ± 14.5 | 76.2 ± 16.8∗ |
Normal saline | 92.4 ± 23.7 | 88.4 ± 16.8 | 84.6 ± 11.3 | 71.4 ± 14.8∗ | |
G-CSF | 101.6 ± 21.2 | 90.2 ± 17.5 | 79.8 ± 19.1∗ | 68.3 ± 17.6∗ | |
Unres/G-CSF | 105.1 ± 12.2 | 93.2 ± 16.1 | 80.8 ± 13.2∗ | 78.3 ± 14.2∗ | |
| |||||
HCT (%) | Blank | 37 ± 5 | 29 ± 7 | 24 ± 2∗ | 21 ± 2∗ |
Normal saline | 34 ± 6 | 26 ± 4 | 23 ± 3∗ | 22 ± 1∗ | |
G-CSF | 38 ± 8 | 24 ± 9∗ | 22 ± 2∗ | 21 ± 1∗ | |
Unres/G-CSF | 39 ± 4 | 25 ± 8∗ | 21 ± 3∗ | 20 ± 2∗ |
Data are mean ± SD. MAP, mean arterial pressure; HR, heart rate; HGB, hemoglobin; HCT, hematocrit. Unres/G-CSF, shocked rats with G-CSF injection without resuscitation.
∗ P < 0.05 versus the values measured before shock and cutaneous injury.