Table 5.
Impact of diabetes to T cells populations in biological prosthesis recipients.
| T cells populations | Healthy donors, n = 48 | Diabetes, n = 3 | No diabetes, n = 22 | p value |
|---|---|---|---|---|
| CD3+% | 78.27 (73.07; 82.52) | 84.21 (65.83; 86.52) | 69.26 (62.71; 74.10) | 1–3 p < 0.001 |
| CD3+ abs. | 1419.31 (1126.25; 1735.91) | 1515.78 (789.96; 1643.88) | 1253.32 (1004.40; 1441.86) | n/s |
| CD3+CD8+% | 25.80 (20.64; 33.20) | 24.95 (24.76; 38.91) | 23.45 (18.07; 27.32) | n/s |
| CD3+CD8+ abs. | 462.37 (349.70; 647.87) | 474.05 (297.12; 700.38) | 408.55 (280.98; 597.77) | n/s |
| CM Tcyt%. | 11.50 (8.70; 16.38) | 6.41 (2.71; 7.50) | 5.99 (3.93; 7.94) | 1–3 p < 0.001 1-2 p = 0.02 |
| CM Tcyt abs. | 51.69 (36.70; 74.30) | 22.28 (18.98; 30.38) | 23.45 (16.15; 31.72) | 1–3 p < 0.001 1-2 p = 0.006 |
| EM Tcyt% | 31.82 (18.80; 43.55) | 42.60 (26.71; 45.43) | 30.56 (18.08; 35.61) | n/s |
| EM Tcyt abs. | 122.56 (74.29; 196.04) | 187.07 (134.98; 201.94) | 118.07 (66.12; 140.10) | 2-3 p = 0.04 |
| TEMRA Tcyt% | 26.67 (19.58; 34.93) | 43.62 (43.46; 68.62) | 49.45 (40.86; 58.83) | 1–3 p < 0.001 1-2 p = 0.009 |
| TEMRA Tcyt abs. | 104.32 (72.94; 188.42) | 206.02 (129.60; 480.60) | 189.40 (126.49; 332.12) | 1–3 p = 0.007 |
| N Tcyt% | 24.46 (16.51; 39.58) | 3.45 (1.96; 7.53) | 13.49 (9.09; 15.83) | 1–3 p < 0.001 1-2 p < 0.001 2-3 p = 0.006 |
| N Tcyt abs. | 98.47 (56.29; 199.74) | 13.72 (10.25; 35.69) | 45.06 (33.37; 64.76) | 1–3 p < 0.001 1-2 p < 0.001 2-3 p = 0.02 |
| CD3+CD4+% | 48.06 (41.04; 52.58) | 45.40 (37.69; 60.29) | 40.72 (36.19; 48.37) | 1–3 p = 0.04 |
| CD3+CD4+ abs. | 835.92 (624.17; 1096.10) | 817.20 (452.28; 1145.51) | 705.31 (580.50; 967.40) | n/s |
| CM Th% | 44.67 (38.42; 49.32) | 47.82 (36.38; 48.95) | 39.46 (35.23; 45.49) | 1–3 p = 0.04 |
| CM Th abs. | 338.29 (269.64; 484.11) | 297.29 (221.39; 547.78) | 257.76 (227.73; 389.99) | 1–3 p = 0.01 |
| EM Th% | 24.02 (17.54; 30.71) | 34.39 (21.28; 43.80) | 25.82 (17.82; 28.86) | n/s |
| EM Th abs. | 197.64 (150.63; 229.90) | 243.76 (155.53; 357.93) | 167.01 (123.98; 233.30) | n/s |
| TEMRA Th% | 0.82 (0.37; 1.67) | 2.26 (0.94; 3.17) | 1.62 (0.90; 2.49) | 1–3 p = 0.006 |
| TEMRA Th abs. | 6.17 (3.11; 13.58) | 18.46 (4.25; 36.31) | 11.23 (6.24; 26.89) | 1–3 p = 0.01 |
| N Th% | 29.88 (19.81; 36.00) | 17.56 (15.72; 27.73) | 33.39 (25.76; 39.09) | 2-3 p = 0.03 |
| N Th abs. | 222.99 (145.88; 369.81) | 143.50 (71.09; 317.64) | 216.69 (140.38; 382.83) | n/s |
| CD4/CD8 | 2.01 (1.34; 2.44) | 1.52 (1.16; 2.41) | 1.96 (1.39; 2.17) | n/s |
n/s: not significant.