Figure 5.

Serotonin reuptake inhibitor (SSRI), fluoxetine, influences both locomotion and feeding behaviors. (a) Fluoxetine significantly decreased body wall contractions. Interestingly, fluoxetine had a greater effect on tryptophan hydroxylase (Trh) mutant animals than w¹¹¹⁸ animals. (b) Fluoxetine significantly reduced mouth hook movements. Fluoxetine, also, had a greater effect on tryptophan hydroxylase (Trh) insertional mutant (homozygous) animals than w¹¹¹⁸ animals. One-way ANOVA was used for comparison, and Bonferroni t-test was employed to compare treatments. Data represented as mean ± SEM.