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. 2016 Mar 2;7:77. doi: 10.3389/fphys.2016.00077

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Copyright © 2016 Hyatt, Nguyen, Hall, Huber, Kocan, Mattison, de Cabo, LaRocque and Talmadge.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Average changes in type I and IIa/x MHC protein isoforms as expressed as a percent of total MHC (top) and type IIa as determined by western analysis (bottom) in EDL muscles of rhesus macaques. Small amounts of MHC type IIb and neonatal (Neo) isoforms were detected in some animals. For westerns blots, each type IIa band was normalized by dividing its density to a control plantaris sample protein band from the same gel. Values are means ± S.E.M. Con-Y, young controls; Con-O, older controls; HFS, high fat/high sugar; HFSR, high fat/high sugar with resveratrol supplementation. ^†Different from Con-O;^‡Different from HFS (P < 0.05).