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. 2016 Mar 2;3:5. doi: 10.3389/fcvm.2016.00005

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Copyright © 2016 Boulaksil, Bierhuizen, Engelen, Stein, Kok, van Amersfoorth, Vos, van Rijen, de Bakker and van Veen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cx43 distribution. (A) Typical examples of anti-Cx43 labeling along with merged photographs of both anti-Cx43 and anti-dystrophin labeling from right and left ventricle (RV/LV) of sham- and TAC-operated rats with or without arrhythmia susceptibility (TAC+/TAC−). Scale bar = 100 μm. (B) Quantifications of heterogeneity of Cx43 distribution are shown (see also Table 2). *P < 0.05 vs. same ventricle; **P < 0.01 vs. same ventricle. (C) Western blot showing Cx43 including the bands for different phosphorylation states in LV myocardial samples from TAC and sham rats. Ponceau S blot is for validation of equal loading. (D) Quantifications of total Cx43 expression, normalized for sham. (E) Quantifications of total Cx43 expression, normalized for cell size (TCSA, Table 2).