Table 3.
Phytophthora cinnamomi genes expressed in planta implicated in pathogenicity or virulence (E-value < 0.01) based on comparison to the plant-host interactions database.
| Gene identity | Average FPKM | Gene ontology | E-value | Gene name | Knock-out phenotype | PHI base accession |
|---|---|---|---|---|---|---|
| e_gw1.822.3.1 | 1443.83 | gi|301096130|ref|XP_002897163.1|Crinkler (CRN) family protein | 3.85E-91 | crn1 | Effector plant avirulence determinant | 656 |
| estExt_fgenesh1_pg.C_680034 | 1323.48 | hydrogen-transporting ATPase activity, rotational mechanism | 9.04E-26 | invC | Reduced virulence | 645 |
| estExt_Genewise1.C_2370044 | 1096.91 | DNA binding | 5.16E-11 | GzLam002 | Reduced virulence | 1533 |
| e_gw1.40.157.1 | 950 | zinc ion binding, glutathione peroxidase activity, response to oxidative stress | 8.14E-35 | MoHYR1 | Reduced virulence | 2356 |
| fgenesh1_kg.2_#_22_#_Locus405v1rpkm794.38 | 915.58 | protein binding, transcription factor binding, GTP binding, ATP binding | 1.40E-67 | CLPT1 | Reduced virulence | 339 |
| e_gw1.76.61.1 | 853.95 | catalytic activity, hydrolase activity, ATP binding, ATPase activity, ATPase activity | 7.85E-55 | PMR1 | Reduced virulence | 440 |
| estExt_Genewise1.C_610064 | 741.59 | protein kinase activity, GTP binding, protein-tyrosine kinase activity | 1.27E-22 | MoSNF1 | Reduced virulence | 1058 |
| fgenesh1_kg.16_#_102_#_Locus840v1rpkm311.24 | 731.62 | catalytic activity, FAD binding, oxidoreductase activity | 3.59E-04 | ALO1 | Reduced virulence | 197 |
| fgenesh1_kg.9_#_117_#_Locus4954v1rpkm35.55 | 647.81 | catalytic activity, cofactor binding, oxidoreductase activity | 4.47E-32 | MGG | Reduced virulence | 881 |
| fgenesh1_pg.124_#_4 | 620.76 | FAD binding, oxidoreductase activity, cell redox homeostasis, electron transport | 7.82E-06 | SID1 | Reduced virulence | 1010 |
| gm1.2704_g | 421.24 | catalytic activity, ATP binding, metabolism | 0.01 | ACL2 | Loss of pathogenicity | 2387 |
| gm1.12073_g | 324.79 | nucleoside triphosphatase activity, nucleotide binding, hydrolase activity | 2.38E-66 | PEX6 | Loss of pathogenicity | 226 |
| gm1.7056_g | 315.86 | catalytic activity, metabolism | 6.30E-17 | SidI | Reduced virulence | 2321 |
| gm1.272_g | 294.34 | catalytic activity, acetate-CoA ligase activity, AMP binding, etabolism | 3.33E-22 | AKT1 | Loss of pathogenicity | 133 |
| e_gw1.31.72.1 | 268.44 | microtubule motor activity, ATP binding, microtubule-based movement | 2.50E-32 | KIN2 | Reduced virulence | 465 |
| e_gw1.1.234.1 | 254.89 | catalytic activity, metabolism | 9.49E-12 | SidI | Reduced virulence | 2321 |
| e_gw1.93.22.1 | 254.29 | protein binding, protein kinase activity, protein-tyrosine kinase activity | 5.50E-22 | Ste11 | Loss of pathogenicity | 2484 |
| e_gw1.1.500.1 | 204.35 | antioxidant activity, oxidoreductase activity | 5.61E-04 | TSA1 | Reduced virulence | 386 |
| estExt_Genemark1.C_2810025 | 203.63 | electron-transferring-flavoprotein dehydrogenase activity, electron transport | 0 | SIDA | Loss of pathogenicity | 486 |
| e_gw1.67.108.1 | 199.31 | ATP binding | 1.08E-57 | LHS1 | Reduced virulence | 2058 |
| e_gw1.82.257.1 | 198.02 | ATP binding | 3.65E-13 | LHS1 | Reduced virulence | 2058 |
| e_gw1.108.166.1 | 195.13 | protein kinase activity, protein-tyrosine kinase activity | 2.83E-66 | MoCMK1 | Reduced virulence | 2158 |
| e_gw1.2.24.1 | 187.23 | helicase activity, nucleic acid binding, ATP dependent helicase activity, ATP binding | 9.73E-70 | VAD1 | Reduced virulence | 423 |
| e_gw1.184.44.1 | 185.29 | protein kinase activity, protein-tyrosine kinase activity, protein serine/threonine kinase activity | 1.67E-51 | SNF1 | Reduced virulence | 188 |
| fgenesh1_pg.86_#_13 | 184.79 | catalytic activity, aspartic-type endopeptidase activity, metabolism | 1.15E-31 | SidI | Reduced virulence | 2321 |
| MIX7251_264_83 | 180.35 | polygalacturonase activity, carbohydrate metabolism | 0 | Pcipg2 | Reduced virulence | 2343 |
| gm1.8946_g | 164.67 | ATP binding, nucleotide binding, nucleoside triphosphatase activity, tRNA ligase activity | 2.70E-47 | ABC4 | Loss of pathogenicity | 2067 |
| e_gw1.2.738.1 | 153.76 | hydrolase activity, cellulose binding, serine-type endopeptidase activity, blood coagulation | 1.21E-46 | CBEL | Effector plant avirulence determinant | 660 |
| fgenesh1_pg.112_#_14 | 142.08 | gi|325187184|emb|CCA21725.1|bromodomain containing 2 putative [Albugo laibachii Nc14] | 1.63E-09 | GzBrom002 | Reduced virulence | 1317 |
| e_gw1.11.45.1 | 137.55 | phosphotransferase activity, alcohol group as acceptor | 1.02E-31 | VPS34 | Loss of pathogenicity | 195 |
| e_gw1.74.48.1 | 116.37 | protein binding, transcription factor binding, GTP binding, ATP binding, GTPase activity | 5.62E-40 | CLPT1 | Reduced virulence | 339 |
| estExt_fgenesh1_pg.C_1470005 | 110.97 | transporter activity, binding, ATPase activity, ATP binding, transport | 1.15E-26 | MgAtr4 | Reduced virulence | 310 |
| gm1.14921_g | 103.14 | motor activity, ATP binding, myosin | 3.16E-114 | GzWing020 | Reduced virulence | 1648 |