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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Radiat Res. 2016 Jan 20;185(2):134–150. doi: 10.1667/RR14035.1

FIG. 7.

FIG. 7

Pretreatment with F15/JP4-039 preserves levels of cellular antioxidants in irradiated oral cavity tissue in tumor-bearing mice. Cellular antioxidant levels (Trolox units) were determined in tissue from the oral cavity of Fancd2+/+ and Fancd2−/− mice 24 h after: 28 Gy single fraction (panel A), 8 Gy × 4 irradiation (panel B) or in TC-1 orthotopic tumors 28 Gy irradiated (panel C). Mice were pretreated with F15 alone, F15/4-amino-Tempo and F15/JP4-039, 15 min before each radiation fraction.