Table 1.
Baseline characteristics
| Characteristic | Value |
|---|---|
| Age, yr | 58.3 ± 15.9 |
| Sex, male | 58 (43.3) |
| Comorbidity | |
| Hypertension | 29 (21.6) |
| Diabetes mellitus | 9 (6.7) |
| Pulmonary tuberculosis | 6 (4.5) |
| Congestive heart failure | 6 (4.5) |
| Myoma | 5 (3.7) |
| Asthma | 4 (2.9) |
| Systemic lupus erythematosus | 3 (2.2) |
| Malignancy | 3 (2.2) |
| Othersa | 11 (8.5) |
| Symptom | |
| Dyspnea | 112 (83.6) |
| Chest pain | 11 (8.2) |
| Abdominal distension | 3 (2.3) |
| Syncope | 2 (1.5) |
| Hemoptysis | 2 (1.5) |
| Weakness | 2 (1.5) |
| Arthralgia | 1 (0.7) |
| Others | 1 (0.7) |
| Risk factor of CTEPH | |
| Prior DVT | 29 (21.6) |
| Prior PTE | 48 (35.8) |
| Prior DVT or PTE | 63 (47) |
| Chronic inflammatory disorderb | 2 (1.5) |
| Autoantibody and thrombotic risk factors | |
| Antinuclear Antibody | 15 (11.6) |
| Rheumatoid factor | 6 (4.5) |
| Antiphospholipid antibody | 7 (5.2) |
| Antithrombin III deficiency | 9 (6.7) |
| Protein C deficiency | 8 (6.0) |
| Protein S deficiency | 6 (4.5) |
| Activated protein C resistance, % | 4 (3.0) |
| Elevated factor VIII | 13 (9.7) |
Values are presented as mean ± SD or number (%). There were no patients with a history of splenectomy or venticuloarterial shunt.
CTEPH, chronic thromboembolic pulmonary hypertension; DVT, deep vein thrombosis; PTE, pulmonary thromboembolism.
a
Others included adrenal insuff iciency, seizure, angina, arrhythmia, valvular heart disease, cerebrovascular accident, intracranial hemorrhage, liver cirrhosis, osteoporosis, Swyer-James’ syndrome.
b
Chronic inflammatory disorder included osteomyelitis and irritable bowel syndrome.