Table 3.
Differences between the distal and proximal chronic thromboembolic pulmonary hypertension groups
| Univariate analysis | Proximal CTEPH (n = 105) | Distal CTEPH (n = 29) | p value |
|---|---|---|---|
| Age, yr | 58.5 ± 16.0 | 57.2 ± 15.8 | 0.702 |
| Sex, male:female | 58:47 | 18:11 | 0.511 |
| NYHA class, I:II:III:IV | 4:36:37:13 | 0:10:8:5 | 0.599 |
| Time from diagnosis, mon | 92.7 ± 47.2 | 129.3 ± 58.9 | 0.008 |
| FEV1/FVC, % | 72.6 ± 9.1 | 80.9 ± 22.6 | 0.025 |
| DLCO, % | 69.8 ± 18.2 | 88.7 ± 22.6 | 0.007 |
| Prior DVT | 22 (23.2) | 7 (25.0) | 0.840 |
| Prior PTE | 38 (39.6) | 10 (35.7) | 0.712 |
| ≥ 1 Segmental perfusion defects | 57 (72.2) | 11 (40.7) | 0.006 |
| Surgery (n = 28) | 25 (25.3) | 3 (10.7) | 0.101 |
| No treatment (n = 5) | 1 (1.0) | 4 (13.8) | 0.008 |
| Death (n = 18) | 14 (13.3) | 4 (13.8) | 0.949 |
Values are presented as or mean ± SD or number (%).
CTEPH, chronic thromboembolic pulmonary hypertension; NYHA, New York Heart Association; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; DLCO, diffuse capacity for carbon monoxide; DVT, deep vein thrombosis; PTE, pulmonary thromboembolism.