Table 2.
Medications prescribed in conjunction with angiotensin-converting enzyme inhibitors or angiotensin II type 1 receptor blockers before and after propensity score matching
| Variable | Before PS match |
After PS match |
||||
|---|---|---|---|---|---|---|
| ACEIs alone (n = 5,951) | ARBs alone (n = 830) | p value | ACEIs alone (n = 2,860) | ARBs alone (n = 715) | p value | |
| Previous medication | ||||||
| Aspirin | 357 (6.0) | 85 (10.2) | < 0.001 | 231 (8.1) | 62 (8.7) | 0.604 |
| Clopidogrel | 95 (1.6) | 25 (3.0) | 0.004 | 57 (2.0) | 18 (2.5) | 0.381 |
| β-Blocker | 261 (4.4) | 51 (6.1) | 0.023 | 146 (5.1) | 40 (5.6) | 0.598 |
| Lipid-lowering drug | 170 (2.9) | 37 (4.5) | 0.012 | 102 (3.6) | 25 (3.5) | 0.928 |
| Calcium channel blocker | 399 (6.7) | 89 (10.7) | < 0.001 | 236 (8.3) | 58 (8.1) | 0.903 |
| Diuretic | 152 (2.6) | 30 (3.6) | 0.077 | 92 (3.2) | 23 (3.2) | 1.000 |
| Nitrate | 158 (2.7) | 30 (3.6) | 0.115 | 81 (2.8) | 23 (3.2) | 0.584 |
| In-hospital medications | ||||||
| Aspirin | 5,908 (99.3) | 823 (99.2) | 0.703 | 2,836 (99.2) | 709 (99.2) | 1.000 |
| Clopidogrel | 5,837 (98.1) | 800 (96.4) | 0.001 | 2,787 (97.4) | 694 (97.1) | 0.565 |
| β-Blocker | 5,072 (85.2) | 596 (71.8) | < 0.001 | 2,252 (78.7) | 560 (78.3) | 0.807 |
| Lipid-lowering drug | 4,839 (81.3) | 662 (79.8) | 0.283 | 2,315 (80.9) | 583 (81.5) | 0.717 |
| Heparin | 4,795 (80.6) | 671 (80.8) | 0.854 | 2,317 (81.0) | 580 (81.1) | 0.949 |
| Calcium channel blocker | 619 (10.4) | 182 (21.9) | < 0.001 | 394 (13.8) | 119 (16.6) | 0.056 |
| Diuretic | 1,697 (28.5) | 344 (41.4) | < 0.001 | 1,072 (37.5) | 273 (38.2) | 0.730 |
| Nitrate | 4,846 (81.4) | 667 (80.4) | 0.459 | 2,307 (80.7) | 579 (81.0) | 0.849 |
| Discharge medication | ||||||
| Aspirin | 5,578 (98.2) | 787 (97.3) | 0.066 | 2,684 (98.0) | 683 (97.6) | 0.488 |
| Clopidogrel | 5,343 (94.1) | 732 (90.5) | < 0.001 | 2,554 (93.2) | 643 (91.9) | 0.200 |
| β-Blocker | 4,597 (80.9) | 557 (68.9) | < 0.001 | 2,044 (74.6) | 515(73.6) | 0.568 |
| Lipid-lowering drug | 4,570 (80.5) | 641 (79.2) | 0.407 | 2,202 (80.4) | 560 (80.0) | 0.815 |
| Calcium channel blocker | 428 (7.5) | 148 (18.3) | < 0.001 | 308 (11.2) | 79 (11.3) | 0.976 |
| Diuretic | 1,136 (20.0) | 264 (32.6) | < 0.001 | 771 (28.1) | 206 (29.4) | 0.503 |
| Nitrate | 3,486 (61.4) | 490 (60.6) | 0.656 | 1,690 (61.7) | 430 (61.4) | 0.895 |
Values are presented as number (%).
PS, propensity score; ACEIs, angiotensin-converting enzyme inhibitors; ARBs, angiotensin II type 1 receptor blockers.