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. 2016 Feb 20;8(2):25. doi: 10.3390/cancers8020025

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© 2016 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) Immunohistochemical expression of Hrh1, Hrh2, Hrh3 and Hrh4 in normal crypts. H & E stain, 400×; (B) Immunohistochemistry of Hrh1, Hrh2, Hrh3 and Hrh4 in adenocarcinomas developed in the mice of Group 1 (AOM + DSS) and (C) Groups 2 (AOM + DSS + terfenadine), 3 (AOM + DSS + cimetidine) and 4 (AOM + DSS + clobenpropit). Immunohistochemistry, 400×.

(A) Immunohistochemical expression of Hrh1, Hrh2, Hrh3 and Hrh4 in normal crypts. H & E stain, 400×; (B) Immunohistochemistry of Hrh1, Hrh2, Hrh3 and Hrh4 in adenocarcinomas developed in the mice of Group 1 (AOM + DSS) and (C) Groups 2 (AOM + DSS + terfenadine), 3 (AOM + DSS + cimetidine) and 4 (AOM + DSS + clobenpropit). Immunohistochemistry, 400×.