Table 2.
Measurement of oxidative stress markers (18-week experiment).
| Group No. | Treatment | No. of Mice Examined | d-ROM a (CARR U b) | BAP a (mM/L) | d-ROM/BAP Ratio |
|---|---|---|---|---|---|
| 1 | AOM + DSS | 20 | 126 ± 11 c | 2931 ± 302 | 0.04361 ± 0.00823 |
| 2 | AOM + DSS + 500 ppm terfenadine | 20 | 133 ± 11 | 2958 ± 470 | 0.04795 ± 0.00591 |
| 3 | AOM + DSS + 500 ppm cimetidine | 20 | 123 ± 26 | 1630 ± 987 | 0.09594 ± 0.05643 |
| 4 | AOM + DSS + 10 ppm clobenpropit | 20 | 131 ± 15 | 2328 ± 1088 | 0.07353 ± 0.02484 |
| 5 | 500 ppm terfenadine | 8 | 138 ± 9 | 2658 ± 909 | 0.04968± 0.01197 |
| 6 | 500 ppm cimetidine | 8 | 130 ± 8 | 2753 ± 1802 | 0.09091 ± 0.08894 |
| 7 | 10 ppm clobenpropit | 8 | 147 ± 10 | 1405 ± 801 | 0.15870 ± 0.06784 |
| 8 | None | 8 | 142 ± 18 | 2477 ± 954 | 0.08182 ± 0.05208 |
a d-ROM = derivatives of reactive oxygen metabolites, and BAP = biological antioxidant potential; b 1 Carr U is equivalent to 0.08 mg H2O2/dL; c Mean ± SD.