Table 1.

Studies included in meta-analysis.

SN	Author	Reference	Country	Ethnicity	Cancer Type	Case/Control	pHWE	MAF	Genotyping Method
DCC rs714 (A > G)
1	Toma et al., 2009	[34]	Romania	Caucasian	CRC	120/60	0.603	0.28	PCR-RFLP
2	Rai et al., 2013	[10]	India	Asian	GBC	406/260	0.062	0.38	PCR-RFLP
3	Malik et al., 2013	[12]	India	Asian	EC	135/195	0.187	0.36	PCR-RFLP
4	Malik et al., 2013	[12]	India	Asian	GC	108/195	0.187	0.36	PCR-RFLP
5	Djansugurova et al., 2015	[13]	Kazakhstan	Mixed	CRC	249/242	0.187	0.36	PCR-RFLP
PSCA rs2294008 (C > T)
1	Wu et al., 2009	[36]	China	Asian	GC	1736/1020	0.587	0.28	PCR-RFLP
2	Matsuo et al., 2009	[27]	Japan	Asian	GC	708/708	0.638	0.38	Taqman
3	Wang et al., 2010	[28]	China	Asian	BC	581/580	0.508	0.27	PCR-RFLP
4	Lu et al., 2010	[37]	China	Asian	GC	1053/1100	0.166	0.25	PCR-RFLP
5	Ou et al., 2010	[38]	China	Asian	GC	196/246	0.924	0.27	PCR-LDR
6	Zeng et al., 2011	[39]	China	Asian	GC	460/549	0.493	0.27	PCR-RFLP
7	Song et al., 2011	[40]	Korea	Asian	GC	3245/1700	0.131	0.48	PCR-RFLP
8	Joung et al., 2011	[41]	Korea	Asian	PC	194/169	0.963	0.47	MASS ARRAY
9	Lochhead et al., 2011	[42]	USA	Caucasian	EC	159/211	0.405	0.5	Taqman
10	Lochhead et al., 2011	[42]	USA	Caucasian	GC	309/211	0.405	0.5	Taqman
11	Sala et al., 2012	[43]	Europe	Caucasian	GC	411/1530	0.088	0.44	SNP ARRAY
12	Kim et al., 2012	[44]	Korea	Asian	BrC	456/461	0.324	0.49	MALDI-TOF MS
13	Smith et al., 2012	[45]	Scotland	Caucasian	CRC	77/804	0.981	0.4	Taqman
14	Li et al., 2012	[46]	China	Asian	GC	300/300	0.65	0.26	MASS-ARRAY IPLEX
15	Ono et al., 2013	[47]	Japan	Asian	GBC	44/173	0.242	0.39	Taqman
16	Ma et al., 2013	[48]	China	Asian	BC	184/962	0.562	0.25	MASS-ARRAY IPLEX
17	Zhao et al., 2013	[35]	China	Asian	GC	717/951	0.913	0.3	PCR-DHPLC
18	Rai et al., 2013	[24]	India	Asian	GBC	405/247	0.492	0.43	Taqman
19	Dai et al., 2014	[49]	China	Asian	EC	2083/2220	0.944	0.27	Taqman
20	Sun et al., 2014	[50]	Texas	Caucasian	GC	132/125	0.926	0.49	Taqman
21	Wang et al., 2014	[51]	China	Asian	BC	1210/1008	0.739	0.25	Taqman
22	Lee et al., 2014	[52]	Korea	Asian	BC	411/1700	0.13	0.48	HRM
23	Kupcinskas et al., 2014	[53]	Lithuania	Caucasian	GC	252/246	0.834	0.48	Taqman
24	Sun et al., 2015	[54]	China	Asian	GC	692/774	0.105	0.28	Taqman
25	MA et al., 2015	[55]	Spain	Caucasian	GC	603/675	0.349	0.45	Taqman
26	Ichikawa et al., 2015	[56]	Japan	Asian	GC	193/266	0.185	0.42	PCR-RFLP
27	Zhang et al., 2015	[57]	China	Asian	GC	476/481	0.617	0.27	MASS ARRAY
28	Kupcinskas et al., 2015	[58]	Latvia	Caucasian	CRC	192/382	0.943	0.48	Taqman
	PSCA rs2976392 (G > A)
1	Wu et al., 2009	[36]	China	Asian	GC	1724/1002	0.35	0.29	PCR-RFLP
2	Matsuo et al., 2009	[27]	Japan	Asian	GC	707/707	0.635	0.37	Taqman
3	Lu et al., 2010	[37]	China	Asian	GC	1043/1082	0.336	0.26	PCR-RFLP
4	Ou et al., 2010	[38]	China	Asian	GC	196/246	0.298	0.26	PCR-LDR
5	Joung et al., 2011	[41]	Korea	Asian	PC	194/168	0.848	0.47	MASS ARRAY
6	Kim et al., 2012	[44]	Korea	Asian	BrC	453/460	0.397	0.49	MALDI-TOF MS
7	Ono et al., 2013	[47]	Japan	Asian	GBC	44/173	0.328	0.61	Taqman
8	Kupcinskas et al., 2014	[53]	Lithuania	Caucasian	GC	249/232	0.986	0.48	Taqman
9	Sun et al., 2015	[54]	China	Asian	GC	692/774	0.13	0.29	Taqman
10	Zhang et al., 2015	[57]	China	Asian	GC	476/481	0.939	0.28	MASS ARRAY
11	Kupcinskas et al., 2015	[58]	Latvia	Caucasian	CRC	192/382	0.856	0.48	Taqman

GC—Gastric cancer, BC—Bladder cancer, GBC—Gallbladder cancer, EC—Esophageal cancer, BrC—Breast Cancer, CRC—Colorectal cancer, PC—Prostate Cancer, HWE Hardy—Weinberg equilibrium, MAF—Minor allelic frequency, PCR—Polymerase chain reaction, RFLP—Restriction fragment length polymorphism, LDR—Ligation detection reaction, DHPLC—Denaturing high performance liquid chromatography, HRM—High-resolution melting, SNP—Single nucleotide polymorphism, MALDI-TOF-MS—Matrix Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry.