Table 2.
Meta-analysis Result for DCC rs714 A > G polymorphism.
| Variables | N | Case/Control | A vs. G Allele | AA vs. GG | GA vs. GG | GA + AA vs. GG | AA vs. GG + GA | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | p | ph/I2 | OR (95% CI) | p | ph/I2 | OR (95% CI) | p | ph/I2 | OR (95% CI) | p | ph/I2 | OR (95% CI) | p | ph/I2 | |||
| All | 5 | 1018/952 | 1.31 (0.93–1.86) | 0.121 | 0.000/84.033 | 1.52 (0.70–3.3) | 0.289 | 0.000/85.434 | 1.37 (0.98–1.92) | 0.068 | 0.032 62.210 | 1.49 (0.98–2.28) | 0.063 | 0.001/79.104 | 1.27 (0.64–2.52) | 0.495 | 0.000/84.117 |
| Ethnicity | |||||||||||||||||
| Caucasian | 1 | 120/60 | 2.14 (1.34–3.43) | 0.002 | 1.000/0.000 | 5.08 (1.56–16.55) | 0.007 | 1.000/0.000 | 2.53 (1.29–4.97) | 0.007 | 1.000/0.000 | 2.87 (1.50–5.50) | 0.001 | 1.000/0.000 | 2.97 (0.97–9.09) | 0.056 | 1.000/0.000 |
| Asian | 3 | 649/650 | 1.41 (1.20–1.66) | 0.000 | 0.810/0.000 | 1.86 (1.35–2.54) | 0.000 | 0.725/0.000 | 1.43 (1.11–1.85) | 0.005 | 0.107 55.174 | 1.66 (1.31–2.09) | 0.000 | 0.182/41.288 | 1.52 (1.14–2.03) | 0.004 | 0.193/39.43 |
| Mixed | 1 | 249/242 | 0.70 (0.54–0.92) | 0.011 | 1.000/0.000 | 0.29 (0.14–0.58) | 0.001 | 1.000/0.000 | 0.99 (0.68–1.44) | 0.975 | 1.000/0.000 | 0.81 (0.57–1.16) | 0.246 | 1.000/0.000 | 0.29 (0.15–0.57) | 0.000 | 1.000/0.000 |
Significant associations are shown in bold, ph—p value of Q test for heterogeneity, OR—Odds Ratio, CI—Confidence Interval.