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Putative roles of claudins in various cancers.
| Type of Claudin | Tumor Suppressor | Oncogene |
|---|---|---|
| Claudin-1 | Lung cancer [93] | Colon cancer [94,95] |
| - | Melanoma [96] | |
| Breast cancer [97] | Breast cancer [97] | |
| Claudin-2 | - | Breast cancer [98,99] |
| Claudin-3 | - | Breast cancer [100,101] |
| Claudin-4 | - | Breast cancer [100,101,102] |
| Claudin-5 | - | Breast cancer [102,103] |
| Claudin-6 | Breast cancer [104] | - |
| Claudin-7 | Breast cancer [105] | Colorectal cancer [106] |
| Claudin-16 | Breast cancer [107] | - |
