Figure 6. M-TNFR1 dependent IL-12 production in granulocytes from M. tuberculosis infected lungs.

(a–c). Intracellular IL-12p40 expression in CD11b⁺ Gr1^high cells, CD11b⁺ Gr1^low cells or in CD3e⁺ cells was represented in WT mice (a) and in M-TNFR1 KO mice (b). Bar graphs (c) summarise IL-12p40 MFI in each cell populations for WT, M-TNFR1-, TNFR1-, or TNFα KO mice. Results are expressed as mean +/− SEM of n = 4–5 mice per group from two independent experiments, with n = 2 TNF KO as references. *p < 0.05; **p < 0.01; ***p < 0.001.