Figure 3. miR-155−/− mice have increased levels of anti-inflammatory cytokines during CVB3-induced VM.
miR-155−/− and WT mice received 1 × 105 PFU of CVB3 i.p. on day 0, and protein levels of IFN-γ, IL-4, IL-13, and IL-17 in the homogenized heart tissue were determined by ELISA on day 7 post-infection. Experiments were repeated three times in triplicate with 8 mice per group. Bar graph data are presented as mean ± SD; *P < 0.05 and **P < 0.01 as compared with WT.