Table 2.

PGI and mean changes from baseline in NRS and EQ-5D utility scores

	n	PGI Effective	dNRS Week 4 (∆)		p	dEQ-5D Week 4 (∆)		p
			Baseline	Week 4 (∆)		Baseline	Week 4 (∆)
Overall	710	614 (86.5)	7.1 [1.9]	−2.7 [2.3]	<0.0001	0.51 [0.20]	0.16 [0.20]	<0.0001
Major the causal disease of pain (multiple allowed)
Osteoarthritis	182	168 (92.3)	7.0 [2.0]	−2.9 [2.3]	<0.0001	0.53 [0.15]	0.17 [0.19]	<0.0001
Lumbago	285	253 (88.8)	7.4 [1.8]	−2.9 [2.4]	<0.0001	0.47 [0.23]	0.19 [0.22]	<0.0001
Rheumatoid arthritis	29	21 (72.4)	6.4 [2.1]	−1.7 [2.0]	0.0002	0.51 [0.18]	0.10 [0.15]	0.0018
Neck, shoulder and arm syndrome	44	38 (86.4)	7.5 [1.7]	−2.8 [2.2]	<0.0001	0.61 [0.14]	0.12 [0.18]	<0.0001
Postherpetic neuralgia	54	46 (85.2)	6.7 [2.1]	−2.9 [2.1]	<0.0001	0.58 [0.17]	0.15 [0.16]	<0.0001
Periarthritis scapulohumeralis	46	39 (84.8)	7.4 [1.8]	−2.2 [1.7]	<0.0001	0.55 [0.13]	0.12 [0.16]	<0.0001
Spinal stenosis	61	47 (77.0)	7.1 [2.0]	−2.5 [2.6]	<0.0001	0.53 [0.10]	0.12 [0.16]	<0.0001
Disk herniation	30	27 (90.0)	6.8 [1.8]	−2.7 [2.4]	<0.0001	0.50 [0.19]	0.17 [0.20]	<0.0001
Others	233	196 (84.1)	6.9 [2.0]	−2.5 [2.6]	<0.0001	0.52 [0.18]	0.13 [0.20]	<0.0001

dEQ-5D denotes change in EuroQol-5D, dNRS change in numeric rating scale, PGI physician’s global impression