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. 2016 Mar 1;15:4. doi: 10.1186/s40200-016-0225-y

Table 3.

Association between SNPs and T2D in the Sudan study population

Chr Gene SNP bp Location A1 N Unadjusted All N Unadjusted Adj Age Adj Age, Sex Adj Age, Sex, BMI
OR L95 U95 P OR L95 U95 P OR L95 U95 P OR L95 U95 P OR L95 U95 P
2 CAPN10 rs2975760 241531413 C 317 0.62 0.31 1.24 0.175 259 0.52 0.25 1.07 0.074 0.42 0.19 0.92 0.030 0.44 0.20 0.96 0.040 0.44 0.20 0.97 0.042
2 CAPN10 rs5030952 241542953 T 314 0.80 0.57 1.12 0.197 257 0.78 0.54 1.15 0.208 0.82 0.55 1.21 0.314 0.80 0.54 1.20 0.280 0.80 0.54 1.19 0.274
3 PPARG rs17036314 12376995 C 300 0.96 0.67 1.38 0.824 242 1.12 0.74 1.71 0.596 1.18 0.75 1.84 0.474 1.14 0.73 1.78 0.558 1.16 0.74 1.81 0.517
3 IGF2BP2 rs4402960 185511937 G 317 0.86 0.63 1.18 0.349 260 0.93 0.66 1.31 0.684 0.93 0.65 1.33 0.693 0.95 0.66 1.35 0.767 0.95 0.66 1.36 0.777
3 IGF2BP2 rs1470579 185529330 A 316 1.01 0.72 1.42 0.959 258 1.02 0.70 1.49 0.924 0.99 0.66 1.46 0.941 1.00 0.68 1.49 0.986 1.02 0.68 1.51 0.930
6 CDKAL1 rs9465871 20717505 C 315 1.27 0.94 1.73 0.120 257 1.17 0.83 1.65 0.376 1.15 0.81 1.65 0.432 1.15 0.80 1.65 0.456 1.15 0.80 1.66 0.443
10 HHEX rs1111875 94463132 A 319 0.71 0.50 1.01 0.060 261 0.68 0.45 1.02 0.060 0.61 0.40 0.94 0.026 0.61 0.40 0.95 0.027 0.60 0.39 0.93 0.022
10 TCF7L2 rs7903146 114758599 T 301 1.69 1.21 2.38 0.002 245 1.62 1.11 2.37 0.013 1.75 1.18 2.61 0.006 1.81 1.21 2.70 0.004 1.79 1.20 2.67 0.005
10 TCF7L2 rs11196205 114807297 G 306 0.78 0.58 1.06 0.117 248 0.68 0.48 0.96 0.029 0.63 0.44 0.91 0.013 0.64 0.44 0.92 0.017 0.64 0.44 0.93 0.018
10 TCF7L2 rs12255372 114809152 T 319 1.70 1.20 2.41 0.003 261 1.53 1.04 2.25 0.031 1.57 1.06 2.33 0.026 1.58 1.07 2.35 0.023 1.60 1.08 2.38 0.021
11 KCNJ11 rs5215 17408880 C 315 1.13 0.69 1.85 0.622 257 0.96 0.56 1.63 0.877 1.02 0.59 1.77 0.944 1.05 0.60 1.84 0.852 1.04 0.60 1.82 0.881
11 KCNJ11 rs5219 17409822 T 316 1.24 0.71 2.16 0.452 258 1.11 0.60 2.06 0.735 1.25 0.66 2.37 0.500 1.31 0.68 2.51 0.419 1.27 0.66 2.45 0.468

Data are presented for an unadjusted analysis for all participants in the study, and for unadjusted and adjusted (as indicated) analyses performed in the subset of individuals for whom complete data on age, sex and BMI was available. Chr = chromosome; bp Location indicates the chromosomal base pair location of the SNP in Genome Reference Consortium Human Build 38 (GRCh38); OR = odds ratio; L95 and U95 indicate lower and upper 95 % confidence intervals. Bold indicates data for SNPs with P<0.05