Table 4.
The effects of multiple SNPs at TCF7L2 on T2D risk in the Sudanese population
| Allele/Haplotype | Frequency | rs7903146 | rs11196205 | rs12255372 |
|---|---|---|---|---|
| T | 0.398 | OR = 1.79; P = 0.005 | ||
| C | 0.567 | OR = 1.56; P = 0.018 | ||
| T | 0.33 | OR = 1.60; P = 0.021 | ||
| TC | 0.377 | OR = 2.24; P = 0.0003 | ||
| CT | 0.294 | OR = 1.86; P = 0.005 | ||
| TCT | 0.236 | OR = 1.86; P = 0.010 | ||
Analysis undertaken under an additive logistic regression model (adjusted for age, sex, and BMI) to look for associations between haplotypes for the 3 SNPs at TCF7L2 and risk of T2D in the Sudanese population. Bold indicates the most significant haplotype association