Table 5.
The effects of multiple SNPs at TCF7L2 on T2D risk in the Sudanese population
| Null model | Alternative model | OR | P-value |
|---|---|---|---|
| rs7903146 | rs7903146 + rs11196205 | 0.98 | 0.938 |
| rs7903146 | rs7903146 + rs12255372 | 1.22 | 0.437 |
| rs11196205 | rs11196205 + rs7903146 | 2.04 | 0.010 |
| rs11196205 | rs11196205 + rs12255372 | 1.53 | 0.078 |
| rs12255372 | rs12255372 + rs7903146 | 1.61 | 0.052 |
| rs12255372 | rs12255372 + rs11196205 | 0.77 | 0.219 |
Stepwise logistic regression analysis to determine whether SNPs at TCF7L2 contribute separate main effects. A significant test comparing null and alternative models indicates that the marker added under the alternative model is contributing a separate main effect from the marker considered under the null hypothesis. Bold indicates nominal P < 0.05