Table 6.
RNAi effector genes discovered in the IJ stage of the H. indica
| S. No. | C. elegans ortholog | H. indica IJ | H. bacteriophora |
|---|---|---|---|
| Small RNA biosynthetic proteins | |||
| Total | 10 | 6 | 2 |
| 1 | drh-3 | + | - |
| 2 | drsh-1 | + | + |
| 3 | xpo-1 | + | - |
| 4 | xpo-2 | + | - |
| 5 | dcr-1 | + | + |
| 6 | drh-1 | + | - |
| dsRNA uptake and spreading and siRNA amplification effectors | |||
| Total | 12 | 4 | 5 |
| 7 | smg-2 | + | + |
| 8 | smg-6 | + | - |
| 9 | ego-1 | + | + |
| 10 | smg-5 | - | + |
| 11 | rsd-3 | + | + |
| 12 | sid-1 | - | + |
| Argonautes (AGOs) | |||
| Total | 28 | 3 | 1 |
| 13 | alg-1 | + | - |
| 14 | rde-1 | - | + |
| 15 | ppw-2 | + | - |
| 16 | nrde-3 | + | - |
| RNA-induced Silencing Complex (RISC) components | |||
| Total | 4 | 2 | 2 |
| 17 | tsn-1 | + | + |
| 18 | ain-1a | + | - |
| 19 | vig-1 | - | + |
| RNAi inhibitors | |||
| Total | 9 | 2 | 0 |
| 20 | eri-1 | + | - |
| 21 | xrn-2 | + | - |
| Nuclear RNAi effectors | |||
| Total | 15 | 7 | 2 |
| 22 | mut-7 | + | - |
| 23 | cid-1 | + | - |
| 24 | gfl-1 | + | + |
| 25 | mes-2 | + | - |
| 26 | rha-1 | + | - |
| 27 | zfp-1 | + | + |
| 28 | mut-2 | + | - |