Skip to main content
. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Cancer Prev Res (Phila). 2015 Oct 28;9(1):43–52. doi: 10.1158/1940-6207.CAPR-14-0287

Figure 5. Glutamine dependence of NAA production in lung cancer cells.

Figure 5

(A) Isotope labeling patterns of NAA in H1299 cells grown in medium containing [U-13C] glucose and unlabeled glutamine (Glc+GLN), or unlabeled glucose and [U-13C] glutamine (Glc+GLN). 13C-labeled aspartate and acetyl-CoA in NAA are marked with asterisks and closed circles, respectively. M+0 indicates unlabeled isotopomer of NAA (m/z=304) while M+X indicates NAA labeled with X carbons from 13C-labeled precursors. Error bars indicate standard errors of normalized metabolite levels (N=3).

(B) Levels of NAA and palmitic acid in H1299 cells under control, glutamine (GLN)-only, or glucose (Glc)-only conditions. Error bars indicate standard errors (N=3).