Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Some prodrug variations based upon amidate linkages
| ||
|---|---|---|
| R1 | R2 | |
| Symmetrical | ||
| Bisamidate | -CHCH3C(O)OCH(CH3)2 | -NH-R1 |
| Monoamidate- monoester | ||
| Amidate/phenyl ester | -CHCH3C(O)OCH(CH3)2 | -OC6H5 |
| Amidate/naphthyl ester | -CHCH3C(O)OCH(CH3)2 | -OC10H7 |
| Amidate/alkyl ester | -(CH2)4Cl (with NCH3) | -OCH2(C4H3NO3) |
| Monoamidates | ||
| Amidate | 2-pyridyl | -OH |
