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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Am J Obstet Gynecol. 2016 Mar;214(3):369.e1–369.e8. doi: 10.1016/j.ajog.2016.01.001

Figure 3. Japanese macaque placental tissue integrity with and without contrast-enhanced ultrasound exposure.

Figure 3

(A) Complement C5b-9 expression in maternal serum obtained at the time of G130 cesarean section delivery, (B) Caspase 3 and (C) Nitrotyrosine protein expression in placental homogenate from control animals who were not exposed to CE-US (white bar) and CE-US exposed (grey bar) animals. Data are mean±SEM for n=6 animals/group. Representative placental tissue sections from a control animal with microbubble exposure during ultrasound stained for (D) Hematoxylin and Eosin (E) TUNEL, where the arrow highlights an apoptosis-positive cell and (F) HSP70, where the arrowhead indicates positive staining on the syncytiotrophoblast. Scale bar indicates 100μm.