Table 1.
List of commonly dysregulated genes in the cortex and hippocampus of transgenic and wild type mice
Fold change | |||||
---|---|---|---|---|---|
Hipocampus | Cortex | ||||
Gene symbol | Entrez gene name | WtVitD/Wt | TgVitD/Tg | WtVitD/Wt | TgVitD/Tg |
Ahcy | adenosylhomocysteinase | −1,73 | −2,07 | 1,79 | 2,07 |
Atg4c | autophagy related 4C, cysteine peptidase | −2,72 | −2,75 | 4,49 | 4,82 |
Avp | arginine vasopressin | −1,59 | 2,21 | 1,73 | 3,96 |
C130078n14 | uncharacterized protein C130078N14 | −2,13 | −2,17 | 3,92 | 2,77 |
Cdk5rap1 | CDK5 regulatory subunit associated protein 1 | −1,78 | −2,14 | 2,66 | 2,92 |
Cpne1 | copine I | −1,56 | −1,82 | 1,6 | 1,71 |
Dnajb8 | DnaJ (Hsp40) homolog, subfamily B, member 8 | −1,85 | 1,98 | −1,92 | −1,73 |
Fam205a | family with sequence similarity 205, member A | 2,34 | 2,78 | 1,61 | −1,55 |
Fkbp1a | FK506 binding protein 1A, 12kDa | 1,97 | 1,62 | −1,72 | −1,52 |
Gbp6 | guanylate binding protein family, member 6 | 2,19 | 2,21 | −2,65 | −3,23 |
Gm4924 | predicted gene 4924 | 1,68 | 1,94 | 2,14 | 1,53 |
Hla-drb5 | major histocompatibility complex, class II, DR beta 5 | 1,86 | 1,53 | −2,53 | −2,34 |
Iqcf4 | IQ motif containing F4 | 2,74 | 2,22 | −1,54 | −1,73 |
Iqsec3 | IQ motif and Sec7 domain 3 | −5,23 | 4,49 | −3,3 | 1,58 |
Kcnj6 | potassium channel, inwardly rectifying subfamily J, member 6 | 1,61 | 1,93 | −1,79 | −1,67 |
Kdr | kinase insert domain receptor | −1,6 | 1,68 | 1,53 | −1,64 |
Mirg | miRNA containing gene | −1,91 | 1,88 | −3,41 | −1,68 |
Nanog | Nanog homeobox | −2,91 | 1,53 | −1,52 | −1,66 |
Ocel1 | occludin/ELL domain containing 1 | −3,07 | −3,98 | 3,52 | 3,21 |
Omp | olfactory marker protein | −1,54 | −10,41 | 3,18 | 1,66 |
Oxt | oxytocin/neurophysin I prepropeptide | −2,75 | 4,04 | 2,03 | 4,74 |
Ppp1r16b | protein phosphatase 1, regulatory subunit 16B | 2,29 | 2,39 | −1,78 | −1,78 |
Prkcd | protein kinase C, delta | −2,18 | −2,52 | 1,84 | 1,65 |
Prl | prolactin | 1,93 | −1,88 | 10,07 | 10,54 |
Rnase4 | ribonuclease, RNase A family, 4 | 1,61 | 2,12 | −2,14 | −2,07 |
Sdc4 | syndecan 4 | 2,38 | 1,95 | −1,91 | −1,81 |
Serpina3g | serine (or cysteine) peptidase inhibitor, clade A, member 3G | 2,78 | 1,94 | −1,8 | −2,42 |
Znf669 | zinc finger protein 669 | −2,08 | −1,9 | 1,84 | 2,2 |
Dysregulated transcripts in the hippocampus and cortex of vitamin D3 supplemented wild type and transgenic mice in comparison with unsupplemented littermates. The gene symbol, the full name and the fold change of each gene are indicated