Table 1.
Measure | Outcomes | Time of collection |
---|---|---|
Baseline recruitment information | Pre-gestational BMI, ethnicity, medical history, age, education, parity, smoking, ongoing supplements | Recruitment visit, 24 wk, and 34 wk |
Maternal anthropometrics | Weight, length, circumference of abdomen, waist etc., skinfold thickness of triceps, subscapularis etc.a | 24 wk, 34 wk |
Bioimpedance | BMRa, impedancea, BMIa, FM/FMIa, FFM/FFMIa, body watera | 24 wk, 34 wk |
Fetal ultrasound | Fetal anthropometricsa | 24 wk, 34 wk |
Urine samples | Metabolomicsa | 24 wk, 34 wk |
Fecal samples | Microbiotab, metabolomicsa | 24 wk, near delivery |
Cheek cell sample | Microbiotaa, geneticsab, fatty acidsa | 34 wk (mother), birth (infant) |
Food questionnaire | Quantitative and qualitative dietary analysesa | 24 wk, 34 wk |
Placenta samples | Placental weight and circumference, Lipid profilea, phospholipidsa, gene expressiona, lipid peroxidation, pTfRb | Delivery |
Lifestyle questionnaire | Lifestyle and physical activitya | 24 wk |
Blood samples (Mother and cord blood) | Direct analyses: ESR, glucose, lipidsa, urea, creatinine, uric acid, bilirubin, iron status, folate, TSH, amylase, CRP, HbA1c, total protein, albumin, vit B12, insulin, cortisol, IGF1a, IGFBP1a, and lymphocyte subpopulationsa. Frozen serum/plasma: Hepcidinb, TfRb, adiponectina, resistina, leptin, interleukinsa, phospholipid profilesa, lipid peroxidationa, tocopherola, retinola. | 24 wk, 34 wk, delivery (mother and cord blood) |
Perinatal records | Gender, gestational age, Apgar, delivery mode, neonatal diagnoses/admission | – |
Infant anthropometrics | Birth weight, length, circumference of head, upper-arm, chest and waist, BMI, waist/height index, heel-knee, hip-knee | Birth |
Meconium | Microbiotaa | Birth |
Breast milk | Fatty acidsa, vitaminsa | day 1, day 7, day 30 |
aUnpublished data
bPublished elsewhere