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. 2016 Mar 1;16:25. doi: 10.1186/s12896-016-0255-z

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© Liu et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Effect of L. lactis NZ9000 (pNZ8148-pIGF-I₃) on colonic occludin level in mice (n = 6) treated with DSS-induced colitis. The statistical differences between groups were evaluated by one-way ANOVA with Duncan’s multiple comparison. Group 1 (control ) received normal drinking water. Group 2 (DSS ) received DSS solution in drinking water. Group 3 (L. lactis ) received the same treatment of DSS as Group 2. Meanwhile, these mice orally administered with L. lactis NZ9000 (pNZ8148). Group 4 (recombinant L. lactis ) received the same treatment of DSS as Group 2. Meanwhile, these mice orally administered with L. lactis NZ9000 (pNZ8148-pIGF-I₃). Same letters between the groups indicate no statistically significant difference (P > 0.05), and different letters indicate statistically significant difference (P < 0.05)

Inline graphic — Effect of L. lactis NZ9000 (pNZ8148-pIGF-I₃) on colonic occludin level in mice (n = 6) treated with DSS-induced colitis. The statistical differences between groups were evaluated by one-way ANOVA with Duncan’s multiple comparison. Group 1 (control ) received normal drinking water. Group 2 (DSS ) received DSS solution in drinking water. Group 3 (L. lactis ) received the same treatment of DSS as Group 2. Meanwhile, these mice orally administered with L. lactis NZ9000 (pNZ8148). Group 4 (recombinant L. lactis ) received the same treatment of DSS as Group 2. Meanwhile, these mice orally administered with L. lactis NZ9000 (pNZ8148-pIGF-I₃). Same letters between the groups indicate no statistically significant difference (P > 0.05), and different letters indicate statistically significant difference (P < 0.05)