Fig. 3.

IL-27 inactivated the JAK/STAT signalling pathway in AEC. a JAK1, STAT1, STAT3 and STAT5 phosphorylated levels were measured by western blot after treatment with IL-27/and TGF-β1 for 1 h. b, c After exposure to a STAT3 specific inhibitor, E-cadherin, β-catenin, vimentin and α--SMA in AECs were measured by real-time PCR and western blot. All data are shown as the mean ± SD (n = 3). Statistical significance was assessed by one-way ANOVA and Tukey’s post hoc test. *P < 0.05; **P < 0.01; ***P < 0.001